Matthijs de Ligt has tested positive for coronavirus, Juventus have confirmed.
Juve were without Juan Cuadrado and Alex Sandro against Milan on Wednesday due to positive COVID-19 tests and the Netherlands international has also entered self-isolation.
The Bianconeri face Sassuolo on Sunday before taking on Genoa and Inter in the following week.
A club statement read: Juventus Football Club announces that, during the checks provided for by the protocol in force, Matthijs de Ligt has emerged positive with COVID-19.
The player has already been placed in self-isolation.
De Ligt missed the start of the 2020-21 season after undergoing shoulder surgery in August but has started 12 straight games in all competitions since returning to action on November 21.